STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADZ10255.1Acetolactate synthase; KEGG: mth:MTH476 pyruvate dehydrogenase / acetolactate synthase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Rubredoxin-type Fe(Cys)4 protein; Thiamine pyrophosphate enzyme, central domain. (585 aa)    
Predicted Functional Partners:
ADZ08346.1
KEGG: mfv:Mfer_0053 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT.
 
 0.992
ADZ08739.1
KEGG: mth:MTH1738 pyruvate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
 
 0.929
ADZ08740.1
KEGG: mmg:MTBMA_c03140 pyruvate synthase, subunit A; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.
  
 
 0.929
ADZ09693.1
KEGG: mmg:MTBMA_c09230 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
 0.929
ADZ09694.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: ppd:Ppro_0548 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
 
 0.929
ADZ10620.1
KEGG: mth:MTH1034 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
 
 0.929
ADZ10621.1
KEGG: mmg:MTBMA_c14150 2-oxoglutarate synthase, subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal.
  
 
 0.929
ADZ10663.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: mmg:MTBMA_c09240 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
 
 0.929
ADZ10664.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: mmg:MTBMA_c09230 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
 0.929
ADZ09015.1
SMART: Biotin carboxylase, C-terminal; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: mmg:MTBMA_c04880 pyruvate carboxylase, subunit A; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal.
  
 
 0.918
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.