STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10268.1KEGG: mmg:MTBMA_c02330 regulatory protein. (167 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
     
 0.651
ADZ10258.1
PUA domain containing protein; KEGG: mst:Msp_1063 RNA-binding protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
 
     0.637
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mfv:Mfer_0095 phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
 
     0.604
ADZ08673.1
Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; KEGG: mmg:MTBMA_c13570 hypothetical protein.
  
     0.582
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.552
ADZ09239.1
PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mmg:MTBMA_c06000 nicotinamide-nucleotide adenylyltransferase.
  
     0.550
ADZ09264.1
UPF0179 protein; KEGG: mmg:MTBMA_c09890 hypothetical protein; HAMAP: Uncharacterised protein family UPF0179; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.
  
   
 0.546
ADZ10265.1
KEGG: mfv:Mfer_0096 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase.
       0.541
ADZ10266.1
TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; KEGG: mfv:Mfer_0097 anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I, C-terminal.
       0.541
ADZ08677.1
HAMAP: HTH transcriptional regulator, cro/C1-type DNA-binding domain-containing; PFAM: Helix-turn-helix type 3; KEGG: mmg:MTBMA_c13530 transcriptional regulator; SMART: Helix-turn-helix type 3.
  
     0.528
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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