Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10321.1Universal PUA-domain-containing protein; TIGRFAM: Conserved hypothetical protein CHP03684; Uncharacterised domain 2; PFAM: Pseudouridine synthase/archaeosine transglycosylase; KEGG: mth:MTH650 putative RNA-binding protein; SMART: Pseudouridine synthase/archaeosine transglycosylase. (146 aa)    
Predicted Functional Partners:
rps28e
KEGG: mst:Msp_0632 30S ribosomal protein S28e; HAMAP: Ribosomal protein S28e, archaeal; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
 
 
 0.892
ADZ10322.1
PFAM: Creatininase; KEGG: mmg:MTBMA_c10310 creatinine amidohydrolase.
       0.878
rps3ae
KEGG: mmg:MTBMA_c01790 30S ribosomal protein S3Ae; HAMAP: 30S ribosomal protein S3Ae; PFAM: Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
   0.782
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
    
 
 0.762
rps4e
HAMAP: Ribosomal protein S4e, archaea; PFAM: Ribosomal protein S4e, central; Ribosomal protein S4e, N-terminal; RNA-binding S4; KEGG: mmg:MTBMA_c05040 30S ribosomal protein S4e; SMART: RNA-binding S4; Belongs to the eukaryotic ribosomal protein eS4 family.
    
 
 0.754
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
   0.742
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 
 0.737
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
    
 
 0.723
rps7
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
    
   0.702
rps19e
Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
 
 
   0.691
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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