Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10322.1PFAM: Creatininase; KEGG: mmg:MTBMA_c10310 creatinine amidohydrolase. (235 aa)    
Predicted Functional Partners:
gch3
GTP cyclohydrolase III; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
    
 0.929
ADZ10344.1
TIGRFAM: Riboflavin-specific deaminase, C-terminal; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; KEGG: mmg:MTBMA_c06840 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal.
    
 0.915
ADZ08491.1
KEGG: mba:Mbar_A1048 5-amino-6-(5-phosphoribosylamino) uracil reductase.
     
  0.900
ADZ10321.1
Universal PUA-domain-containing protein; TIGRFAM: Conserved hypothetical protein CHP03684; Uncharacterised domain 2; PFAM: Pseudouridine synthase/archaeosine transglycosylase; KEGG: mth:MTH650 putative RNA-binding protein; SMART: Pseudouridine synthase/archaeosine transglycosylase.
       0.878
ADZ09104.1
PFAM: Glycosyl transferase, family 2; KEGG: has:Halsa_0644 undecaprenyl-phosphate galactose phosphotransferase.
  
  
 0.658
ADZ09890.1
PFAM: Glycosyl transferase, family 2; KEGG: mem:Memar_1704 glycosyl transferase family protein.
  
  
 0.658
ADZ10653.1
TIGRFAM: Putative methanogenesis marker domain 9; KEGG: mth:MTH1014 hypothetical protein.
  
    0.419
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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