Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10325.1PFAM: Thioesterase superfamily; KEGG: mmg:MTBMA_c10390 thioesterase. (139 aa)    
Predicted Functional Partners:
ADZ10324.1
Long-chain-fatty-acid--CoA ligase; KEGG: mth:MTH657 AMP-binding domain protein; PFAM: AMP-dependent synthetase/ligase.
 
  
 0.883
ADZ10326.1
KEGG: mmz:MmarC7_1587 helix-turn-helix domain-containing protein; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3.
  
  
 0.845
ADZ10667.1
PFAM: 4Fe-4S binding domain; KEGG: mmq:MmarC5_0318 ketoisovalerate ferredoxin oxidoreductase, delta subunit.
 
  
 0.554
ilvD
PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: mmg:MTBMA_c00370 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
  
 0.537
ADZ08530.1
Long-chain-fatty-acid--CoA ligase; KEGG: shi:Shel_23800 AMP-forming long-chain acyl-CoA synthetase; PFAM: Male sterility, NAD-binding; AMP-dependent synthetase/ligase.
 
  
 0.521
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.460
ADZ10645.1
PFAM: MotA/TolQ/ExbB proton channel; KEGG: mmg:MTBMA_c14040 biopolymer transport protein.
 
  
 0.434
ADZ10685.1
PFAM: MotA/TolQ/ExbB proton channel; KEGG: mmg:MTBMA_c10530 transporter protein.
 
  
 0.427
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
 
 
 0.426
ADZ09915.1
KEGG: mmg:MTBMA_c10530 transporter protein.
 
  
 0.421
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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