STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10344.1TIGRFAM: Riboflavin-specific deaminase, C-terminal; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; KEGG: mmg:MTBMA_c06840 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. (226 aa)    
Predicted Functional Partners:
ADZ10322.1
PFAM: Creatininase; KEGG: mmg:MTBMA_c10310 creatinine amidohydrolase.
    
 0.926
ADZ08299.1
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
 
 0.915
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.914
ADZ08491.1
KEGG: mba:Mbar_A1048 5-amino-6-(5-phosphoribosylamino) uracil reductase.
     
  0.900
ADZ09015.1
SMART: Biotin carboxylase, C-terminal; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: mmg:MTBMA_c04880 pyruvate carboxylase, subunit A; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal.
   
   0.702
prf1
Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
   
   0.693
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
  
  
 0.514
ADZ10345.1
PFAM: Carboxymuconolactone decarboxylase; KEGG: sml:Smlt1304 putative 4-carboxymuconolactone decarboxylase.
       0.471
ADZ10346.1
KEGG: mfv:Mfer_0596 hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; PFAM: Deoxyribonuclease, TatD-related.
   
   0.466
ADZ08556.1
TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; KEGG: mth:MTH1216 pantothenate metabolism flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein.
 
   
 0.427
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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