Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10348.1Methanogen marker protein 4; TIGRFAM: Methyltransferase Mtx, subunit X; KEGG: mfv:Mfer_0594 methanogen marker protein 4. (241 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
  
    0.838
ADZ08605.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
  
   
 0.771
ADZ10346.1
KEGG: mfv:Mfer_0596 hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; PFAM: Deoxyribonuclease, TatD-related.
       0.765
ADZ08427.1
Methanogenesis marker protein 11; KEGG: msi:Msm_1295 DNA-binding protein; TIGRFAM: Putative methanogenesis marker protein 11; PFAM: Domain of unknown function DUF1743.
 
     0.749
ADZ10652.1
SMART: ATPase, AAA+ type, core; TIGRFAM: Methyl coenzyme M reductase system, component A2; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; PFAM: ABC transporter-like.
  
   
 0.740
ADZ08598.1
Methanogenesis marker protein 7; TIGRFAM: Uncharacterised conserved protein UCP019164, methanogenesis; KEGG: mmg:MTBMA_c15570 methyl coenzyme M reductase II, operon protein C.
 
     0.738
ADZ10495.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
  
   
 0.736
ADZ08935.1
UPF0288 protein; KEGG: mmg:MTBMA_c04360 peptidyl-prolyl cis-trans isomerase related protein; TIGRFAM: Uncharacterised protein family UPF0288, methanogenesis; HAMAP: Uncharacterised protein family UPF0288, methanogenesis; Belongs to the UPF0288 family.
  
   
 0.734
ADZ08938.1
Methanogenesis marker protein 5; KEGG: mth:MTH1868 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP018781, methanogenesis; PFAM: Uncharacterised conserved protein UCP018781, methanogenesis.
  
     0.732
ADZ08760.1
TIGRFAM: Methyl coenzyme M reductase system, component A2; PFAM: ABC transporter-like; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; SMART: ATPase, AAA+ type, core.
  
   
 0.731
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.