Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10368.1Type II site-specific deoxyribonuclease; KEGG: abi:Aboo_1333 protein of unknown function DUF450; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; DNA methylase, adenine-specific. (1021 aa)    
Predicted Functional Partners:
ADZ09784.1
KEGG: mbu:Mbur_2162 helicase-like protein; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.
 
     0.947
ADZ09893.1
PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: mth:MTH912 hypothetical protein.
 
     0.936
ADZ09358.1
PFAM: DNA methylase, adenine-specific; KEGG: mmq:MmarC5_1169 N-6 DNA methylase.
 
  
 0.846
ADZ08991.1
PFAM: Fibronectin-binding A, N-terminal; Domain of unknown function DUF814; KEGG: mmg:MTBMA_c04780 hypothetical protein.
  
    0.825
ADZ08706.1
Beta-lactamase domain protein; KEGG: mmg:MTBMA_c14810 hydrolase; PFAM: Beta-lactamase-like; Rhodanese-like; SMART: Beta-lactamase-like; Rhodanese-like.
       0.777
ADZ09297.1
KEGG: mpl:Mpal_2117 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like.
       0.777
ADZ10367.1
KEGG: tye:THEYE_A0521 hypothetical protein.
       0.773
rnj
Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
       0.771
ADZ09362.1
Putative transcriptional regulator; PFAM: ATPase, AAA-4; KEGG: mac:MA2370 ATP-dependent DNA helicase.
 
     0.665
ADZ09359.1
PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: mmw:Mmwyl1_3199 restriction modification system DNA specificity subunit.
 
  
 0.663
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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