Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADZ10401.1Shwachman-Bodian-Diamond syndrome protein; KEGG: mth:MTH685 putative RNA-associated protein; TIGRFAM: Ribosome maturation protein SBDS; PFAM: Ribosome maturation protein SBDS, N-terminal; Ribosome maturation protein SBDS, C-terminal. (230 aa)    
Predicted Functional Partners:
rpl37ae
50S ribosomal protein L37Ae; Binds to the 23S rRNA.
  
   0.979
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.972
rps9
KEGG: mth:MTH39 ribosomal protein S16; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.967
rpl15e
KEGG: mmg:MTBMA_c10770 50S ribosomal protein L15e; HAMAP: Ribosomal protein L15e, archaeal; PFAM: Ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 
 0.958
ADZ09054.1
KEGG: mst:Msp_0880 50S ribosomal protein L14e.
  
 
 0.953
psmA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
  
 0.953
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
 
 
 0.951
rpl30
KEGG: mmg:MTBMA_c05130 50S ribosomal protein L30P; TIGRFAM: Ribosomal protein L30, archaeal; PFAM: Ribosomal protein L30, ferredoxin-like fold domain.
 
 
 0.928
ADZ10159.1
Hypothetical protein.
  
   0.926
rps28e
KEGG: mst:Msp_0632 30S ribosomal protein S28e; HAMAP: Ribosomal protein S28e, archaeal; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
 
 0.923
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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