Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10408.1TIGRFAM: Riboflavin synthase, archaeal; KEGG: mst:Msp_1239 riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase. (152 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
  
 0.976
ADZ08298.1
Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK.
    
  0.927
ADZ08299.1
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
   
 0.851
ribL
Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
 
     0.600
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
       0.571
ADZ10348.1
Methanogen marker protein 4; TIGRFAM: Methyltransferase Mtx, subunit X; KEGG: mfv:Mfer_0594 methanogen marker protein 4.
  
     0.562
ADZ08815.1
Serine--pyruvate transaminase; KEGG: mmg:MTBMA_c01880 aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase.
       0.541
ADZ10305.1
UPF0235 protein yggU; TIGRFAM: Conserved hypothetical protein CHP00251; HAMAP: Protein of unknown function DUF167; KEGG: mmg:MTBMA_c10190 hypothetical protein; PFAM: Protein of unknown function DUF167; Belongs to the UPF0235 family.
 
     0.536
ADZ09216.1
PFAM: Glycosyl transferase, family 2; KEGG: mmg:MTBMA_c05860 glycosyltransferase.
       0.526
ADZ08937.1
PFAM: Uncharacterised conserved protein UCP006557, signal transduction; KEGG: mfv:Mfer_1093 hypothetical protein.
  
     0.481
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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