Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10412.1PFAM: Uncharacterised conserved protein UCP006577; KEGG: mru:mru_1621 hypothetical protein. (102 aa)    
Predicted Functional Partners:
ADZ10413.1
PFAM: Uncharacterised conserved protein UCP006600; KEGG: msi:Msm_0104 hypothetical protein.
       0.918
ADZ10411.1
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mth:MTH775 methionine synthase.
 
     0.902
thyA
Thymidylate synthase, methanogen type; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
 
     0.826
ADZ08615.1
Methanogenesis marker protein 14; KEGG: mth:MTH1153 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP016937, methanogenesis; PFAM: Uncharacterised conserved protein UCP016937, methanogenesis.
 
     0.783
ADZ08600.1
Methanogenesis marker protein 10; KEGG: mmg:MTBMA_c15530 Fe-S oxidoreductase; TIGRFAM: Putative methanogenesis marker protein 10; PFAM: Domain of unknown function DUF512; Radical SAM.
  
     0.756
mtrE
Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.756
mtrC
Tetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.756
mtrG
Tetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.755
mtrD
Tetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.754
ADZ10653.1
TIGRFAM: Putative methanogenesis marker domain 9; KEGG: mth:MTH1014 hypothetical protein.
  
     0.753
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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