Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10415.1KEGG: mmg:MTBMA_c11780 hydrogenase maturation factor HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like. (217 aa)    
Predicted Functional Partners:
hypA
Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.999
ADZ10477.1
KEGG: mmg:MTBMA_c14600 hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein.
 
  
 0.969
ADZ08484.1
Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.
 
   
 0.961
ADZ08470.1
TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.916
ADZ10269.1
Hydrogenase assembly chaperone hypC/hupF; KEGG: mmg:MTBMA_c02320 hydrogenase maturation factor HypC; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC.
 
  
 0.875
ADZ09518.1
NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c07980 energy-converting hydrogenase A, subunit O; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit.
   
 
 0.869
ADZ10455.1
PFAM: Putative Fe-S cluster; KEGG: mmg:MTBMA_c02500 hypothetical protein.
 
    0.854
ADZ10383.1
KEGG: mth:MTH205 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein.
 
  
 0.843
ADZ10457.1
ABC transporter related protein; KEGG: mth:MTH1673 sn-glycerol-3-phosphate transport ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
  
  
 0.842
ADZ10458.1
TIGRFAM: Phosphosulpholactate synthase; KEGG: mth:MTH1674 hypothetical protein; PFAM: (2R)-phospho-3-sulpholactate synthase, ComA.
  
    0.830
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.