STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (128 aa)    
Predicted Functional Partners:
ADZ08470.1
TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.999
ADZ08484.1
Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.
 
   
 0.999
ADZ10415.1
KEGG: mmg:MTBMA_c11780 hydrogenase maturation factor HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like.
 
 
 0.999
ADZ08622.1
Hydrogen dehydrogenase; KEGG: mmg:MTBMA_c15170 F420-non-reducing hydrogenase, subunit A; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.932
ADZ08890.1
Hydrogen dehydrogenase; KEGG: mpd:MCP_2492 F420-non-reducing hydrogenase subunit A; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.931
ADZ10477.1
KEGG: mmg:MTBMA_c14600 hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein.
 
  
 0.908
ADZ10456.1
PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; KEGG: mth:MTH1672 hypothetical protein.
 
 
 0.894
ADZ09730.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
 
 0.820
ADZ10383.1
KEGG: mth:MTH205 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein.
 
  
 0.812
ADZ08525.1
NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c16260 energy-converting hydrogenase B, subunit N; PFAM: Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D.
  
 
 0.790
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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