Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADZ10423.1Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c11350 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core. (133 aa)    
Predicted Functional Partners:
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.899
rps9
KEGG: mth:MTH39 ribosomal protein S16; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.899
ADZ08548.1
Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16090 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
 
    0.827
ADZ10446.1
Putative signal transduction protein with CBS domains; KEGG: mth:MTH992 inosine-5'-monophosphate dehydrogenase related protein IX; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
 
    0.771
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
 
 0.762
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.753
ADZ08953.1
PFAM: Protein of unknown function DUF749; KEGG: msi:Msm_0794 hypothetical protein.
  
    0.752
rps13
Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
  
 
 0.749
rps2
KEGG: mth:MTH44 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.749
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
 
   0.748
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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