| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08470.1 | ADZ08484.1 | Metbo_0218 | Metbo_0232 | TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. | 0.954 |
| ADZ08470.1 | ADZ10426.1 | Metbo_0218 | Metbo_2212 | TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | KEGG: mmg:MTBMA_c11320 hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogenase maturation protease HycI; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. | 0.595 |
| ADZ08470.1 | hypA | Metbo_0218 | Metbo_2202 | TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.976 |
| ADZ08484.1 | ADZ08470.1 | Metbo_0232 | Metbo_0218 | Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. | TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.954 |
| ADZ08484.1 | ADZ08525.1 | Metbo_0232 | Metbo_0273 | Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. | NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c16260 energy-converting hydrogenase B, subunit N; PFAM: Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D. | 0.586 |
| ADZ08484.1 | ADZ09518.1 | Metbo_0232 | Metbo_1276 | Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. | NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c07980 energy-converting hydrogenase A, subunit O; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit. | 0.708 |
| ADZ08484.1 | ADZ10426.1 | Metbo_0232 | Metbo_2212 | Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. | KEGG: mmg:MTBMA_c11320 hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogenase maturation protease HycI; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. | 0.548 |
| ADZ08484.1 | hypA | Metbo_0232 | Metbo_2202 | Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.966 |
| ADZ08525.1 | ADZ08484.1 | Metbo_0273 | Metbo_0232 | NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c16260 energy-converting hydrogenase B, subunit N; PFAM: Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D. | Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. | 0.586 |
| ADZ08525.1 | ADZ10426.1 | Metbo_0273 | Metbo_2212 | NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c16260 energy-converting hydrogenase B, subunit N; PFAM: Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D. | KEGG: mmg:MTBMA_c11320 hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogenase maturation protease HycI; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. | 0.575 |
| ADZ08525.1 | hypA | Metbo_0273 | Metbo_2202 | NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c16260 energy-converting hydrogenase B, subunit N; PFAM: Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D. | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.684 |
| ADZ09518.1 | ADZ08484.1 | Metbo_1276 | Metbo_0232 | NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c07980 energy-converting hydrogenase A, subunit O; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit. | Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. | 0.708 |
| ADZ09518.1 | ADZ10426.1 | Metbo_1276 | Metbo_2212 | NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c07980 energy-converting hydrogenase A, subunit O; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit. | KEGG: mmg:MTBMA_c11320 hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogenase maturation protease HycI; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. | 0.548 |
| ADZ09518.1 | hypA | Metbo_1276 | Metbo_2202 | NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c07980 energy-converting hydrogenase A, subunit O; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit. | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.765 |
| ADZ09730.1 | ADZ10426.1 | Metbo_1498 | Metbo_2212 | ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | KEGG: mmg:MTBMA_c11320 hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogenase maturation protease HycI; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. | 0.547 |
| ADZ09730.1 | hypA | Metbo_1498 | Metbo_2202 | ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.907 |
| ADZ10424.1 | ADZ10425.1 | Metbo_2210 | Metbo_2211 | Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | PFAM: Methyltransferase type 12; KEGG: mfv:Mfer_1049 RNA methylase. | 0.847 |
| ADZ10424.1 | ADZ10426.1 | Metbo_2210 | Metbo_2212 | Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | KEGG: mmg:MTBMA_c11320 hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogenase maturation protease HycI; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. | 0.878 |
| ADZ10424.1 | ADZ10427.1 | Metbo_2210 | Metbo_2213 | Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | PFAM: ATP-grasp fold, DUF201-type; KEGG: mst:Msp_1215 hypothetical protein. | 0.555 |
| ADZ10424.1 | ADZ10428.1 | Metbo_2210 | Metbo_2214 | Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | KEGG: mth:MTH735 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site. | 0.419 |
