Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10430.1KEGG: mru:mru_2092 cell wall biosynthesis protein Mur ligase family; PFAM: Mur ligase, central. (470 aa)    
Predicted Functional Partners:
ADZ10431.1
Mur ligase middle domain protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; KEGG: msi:Msm_1190 UDP-N-acetylmuramate-alanine ligase.
 
    
0.924
ADZ10428.1
KEGG: mth:MTH735 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site.
 
     0.734
ADZ10429.1
Mur ligase middle domain protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; KEGG: mfv:Mfer_0762 mur ligase middle domain protein.
 
    
0.596
ADZ10031.1
APHP domain protein; PFAM: APHP; Succinylglutamate desuccinylase/aspartoacylase; KEGG: mka:MK1596 aminoacylase-2/carboxypeptidase Z family hydrolase.
  
     0.551
ADZ10278.1
KEGG: mfv:Mfer_0066 cell wall biosynthesis protein.
  
     0.510
ADZ10432.1
KEGG: mmg:MTBMA_c11280 hypothetical protein.
       0.508
ADZ10433.1
KEGG: mmg:MTBMA_c11270 hypothetical protein.
       0.508
ADZ10427.1
PFAM: ATP-grasp fold, DUF201-type; KEGG: mst:Msp_1215 hypothetical protein.
 
     0.506
ADZ10382.1
PFAM: RDD; KEGG: mfv:Mfer_1285 rdd domain containing protein.
  
     0.468
ADZ08841.1
KEGG: mmg:MTBMA_c02720 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII.
  
     0.425
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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