STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10443.1KEGG: mfv:Mfer_0461 S-adenosylhomocysteine deaminase; PFAM: Amidohydrolase 1. (383 aa)    
Predicted Functional Partners:
carB
SMART: Methylglyoxal synthase-like domain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; KEGG: mmg:MTBMA_c13790 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; Belongs to the CarB family.
  
  
 0.666
ADZ10445.1
PFAM: UspA; KEGG: mmg:MTBMA_c13760 universal stress protein.
       0.603
carA
TIGRFAM: Carbamoyl-phosphate synthase, small subunit; KEGG: mmg:MTBMA_c13800 carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family.
  
    0.538
serS
Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
       0.528
ADZ10446.1
Putative signal transduction protein with CBS domains; KEGG: mth:MTH992 inosine-5'-monophosphate dehydrogenase related protein IX; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
 
     0.473
ADZ08261.1
PFAM: Amidohydrolase 1; KEGG: mfv:Mfer_0494 amidohydrolase.
 
  
 0.446
ADZ08807.1
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
 
  
 0.430
ADZ08635.1
TIGRFAM: Uracil phosphoribosyl transferase; KEGG: mmg:MTBMA_c14980 uracil phosphoribosyltransferase.
  
  
 0.424
ADZ10427.1
PFAM: ATP-grasp fold, DUF201-type; KEGG: mst:Msp_1215 hypothetical protein.
 
  
 0.418
ADZ09541.1
KEGG: cpy:Cphy_3485 peptidase T-like protein; TIGRFAM: Peptidase M20B, peptidase T; PFAM: Peptidase M20, dimerisation; Peptidase M20.
 
  
 0.417
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.