Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10448.1TIGRFAM: Conserved hypothetical protein CHP00268; KEGG: mmg:MTBMA_c13730 ATP-utilizing enzyme. (349 aa)    
Predicted Functional Partners:
ADZ10633.1
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; PFAM: Phosphoribosylaminoimidazole carboxylase, core; Protein of unknown function DUF2089; KEGG: msi:Msm_1105 NCAIR mutase related protein, PurE.
 
  
 0.967
ADZ08643.1
UPF0272 protein; TIGRFAM: Uncharacterised protein family UPF0272; HAMAP: Uncharacterised protein family UPF0272; KEGG: mth:MTH1109 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; Belongs to the LarC family.
  
 0.944
ADZ10449.1
PFAM: TfuA-like, core; KEGG: mmg:MTBMA_c13720 hypothetical protein.
       0.672
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
    0.606
ADZ08325.1
PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; KEGG: mru:mru_0539 cobalamin biosynthesis protein CbiM1.
 
    0.588
ADZ08326.1
KEGG: mth:MTH1706 cobalt transport protein CbiN.
  
    0.521
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.521
mutS2
DNA mismatch repair protein MutS domain protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
       0.459
ADZ08310.1
PFAM: 4Fe-4S binding domain; KEGG: mth:MTH1826 hypothetical protein.
 
    0.454
ADZ09598.1
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
    0.419
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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