Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10456.1PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; KEGG: mth:MTH1672 hypothetical protein. (233 aa)    
Predicted Functional Partners:
ADZ10457.1
ABC transporter related protein; KEGG: mth:MTH1673 sn-glycerol-3-phosphate transport ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
 
  
 0.996
ADZ10455.1
PFAM: Putative Fe-S cluster; KEGG: mmg:MTBMA_c02500 hypothetical protein.
 
    0.992
ADZ10458.1
TIGRFAM: Phosphosulpholactate synthase; KEGG: mth:MTH1674 hypothetical protein; PFAM: (2R)-phospho-3-sulpholactate synthase, ComA.
  
    0.983
hypA
Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.919
ADZ10477.1
KEGG: mmg:MTBMA_c14600 hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein.
  
  
 0.813
ADZ08627.1
PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: mmg:MTBMA_c15080 peptidyl-prolyl cis-trans isomerase.
    
 
 0.731
ADZ10269.1
Hydrogenase assembly chaperone hypC/hupF; KEGG: mmg:MTBMA_c02320 hydrogenase maturation factor HypC; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC.
  
  
 0.700
ADZ08525.1
NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c16260 energy-converting hydrogenase B, subunit N; PFAM: Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D.
   
 
 0.672
ADZ09518.1
NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c07980 energy-converting hydrogenase A, subunit O; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit.
   
 
 0.672
ADZ10454.1
Protein of unknown function DUF129; PFAM: F420-0 gamma-glutamyl ligase-related; KEGG: mth:MTH1670 hypothetical protein.
       0.659
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.