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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10496.1PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mac:MA2764 TetR family transcriptional regulator. (236 aa)    
Predicted Functional Partners:
ADZ10497.1
PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type.
 
     0.520
ADZ09616.1
PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mpi:Mpet_1090 TetR family transcriptional regulator.
  
     0.479
ADZ10493.1
KEGG: mst:Msp_0319 MrtD; TIGRFAM: Methyl-coenzyme M reductase, protein D; PFAM: Methyl-coenzyme M reductase, protein D.
       0.444
ADZ10494.1
TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1130 methyl coenzyme M reductase II, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.
       0.430
ADZ10495.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
       0.430
ADZ09648.1
PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mac:MA0368 TetR family transcriptional regulator.
  
     0.422
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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