Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10499.1PFAM: NADPH-dependent FMN reductase; KEGG: mem:Memar_0225 NADPH-dependent FMN reductase. (188 aa)    
Predicted Functional Partners:
ADZ08468.1
TIGRFAM: Conserved hypothetical protein CHP00061; KEGG: mmg:MTBMA_c16880 hypothetical protein.
  
    0.810
ADZ10501.1
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: mmg:MTBMA_c01800 FeMo cofactor biosynthesis protein.
     
 0.782
ADZ10500.1
PFAM: Methyltransferase type 12; KEGG: sen:SACE_0718 TDP-desosamine-N-dimethyltransferase.
 
 
 0.774
ADZ09692.1
PFAM: NADPH-dependent FMN reductase; KEGG: mac:MA3658 iron-sulfur flavoprotein.
  
     0.688
ADZ10502.1
Flavodoxin; KEGG: cbe:Cbei_3563 flavodoxin.
     
 0.574
ADZ09613.1
PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: mth:MTH1097 hypothetical protein.
 
  
 0.559
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
  
 0.555
ADZ10200.1
PFAM: 4Fe-4S binding domain; KEGG: bpo:BP951000_2164 4Fe-4S ferredoxin-domain-containing protein.
  
    0.540
ADZ09051.1
PFAM: Protein of unknown function DUF106, transmembrane; KEGG: mmg:MTBMA_c05170 hypothetical protein.
   
    0.464
aroA-2
Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
 
  
 0.456
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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