STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10539.1PFAM: BioY protein; KEGG: mmg:MTBMA_c12990 biotin biosynthesis protein. (206 aa)    
Predicted Functional Partners:
ecfA
Cobalt ABC transporter, ATPase subunit; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 
 0.964
ADZ10538.1
PFAM: Protein of unknown function DUF1284; KEGG: mev:Metev_1512 hypothetical protein.
 
    0.913
ADZ08327.1
Cobalt ABC transporter, inner membrane subunit CbiQ; KEGG: mru:mru_0541 cobalt ABC transporter permease protein CbiQ1; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein.
 
 
 0.909
ADZ09005.1
KEGG: mfv:Mfer_0953 cobalt abc transporter, inner membrane subunit CbiQ; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein.
  
 
 0.875
ADZ09014.1
TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; KEGG: mmg:MTBMA_c04870 biotin ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal.
 
   
 0.674
ADZ08565.1
KEGG: mfv:Mfer_1224 radical sam domain protein; PFAM: Radical SAM; Biotin/thiamin synthesis-associated protein; SMART: Elongator protein 3/MiaB/NifB.
 
  
 0.660
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
  
  
 0.645
ADZ10537.1
KEGG: mfv:Mfer_0933 hypothetical protein.
       0.461
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
       0.449
ADZ10540.1
PFAM: Domain of unknown function DUF523; Domain of unknown function DUF1722; KEGG: mac:MA4104 hypothetical protein.
       0.429
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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