| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08756.1 | ADZ10542.1 | Metbo_0504 | Metbo_2329 | TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: mmg:MTBMA_c03260 Fe-S oxidoreductase; SMART: Elongator protein 3/MiaB/NifB. | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | 0.638 |
| ADZ08830.1 | ADZ09610.1 | Metbo_0579 | Metbo_1370 | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | Thermosome; KEGG: mmg:MTBMA_c06670 thermosome, subunit alpha (chaperonin subunit); TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | 0.855 |
| ADZ08830.1 | ADZ10121.1 | Metbo_0579 | Metbo_1901 | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | Thermosome; KEGG: mth:MTH794 chaperonin; TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | 0.855 |
| ADZ08830.1 | ADZ10542.1 | Metbo_0579 | Metbo_2329 | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | 0.619 |
| ADZ08830.1 | dnaK | Metbo_0579 | Metbo_0229 | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | Chaperone protein dnaK; Acts as a chaperone. | 0.890 |
| ADZ08830.1 | grpE | Metbo_0579 | Metbo_0230 | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.667 |
| ADZ09610.1 | ADZ08830.1 | Metbo_1370 | Metbo_0579 | Thermosome; KEGG: mmg:MTBMA_c06670 thermosome, subunit alpha (chaperonin subunit); TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | 0.855 |
| ADZ09610.1 | ADZ10542.1 | Metbo_1370 | Metbo_2329 | Thermosome; KEGG: mmg:MTBMA_c06670 thermosome, subunit alpha (chaperonin subunit); TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | 0.699 |
| ADZ09610.1 | dnaG | Metbo_1370 | Metbo_2330 | Thermosome; KEGG: mmg:MTBMA_c06670 thermosome, subunit alpha (chaperonin subunit); TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.609 |
| ADZ09610.1 | dnaK | Metbo_1370 | Metbo_0229 | Thermosome; KEGG: mmg:MTBMA_c06670 thermosome, subunit alpha (chaperonin subunit); TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | Chaperone protein dnaK; Acts as a chaperone. | 0.981 |
| ADZ09610.1 | grpE | Metbo_1370 | Metbo_0230 | Thermosome; KEGG: mmg:MTBMA_c06670 thermosome, subunit alpha (chaperonin subunit); TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.963 |
| ADZ09610.1 | tuf | Metbo_1370 | Metbo_2389 | Thermosome; KEGG: mmg:MTBMA_c06670 thermosome, subunit alpha (chaperonin subunit); TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.492 |
| ADZ10121.1 | ADZ08830.1 | Metbo_1901 | Metbo_0579 | Thermosome; KEGG: mth:MTH794 chaperonin; TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | 0.855 |
| ADZ10121.1 | ADZ10542.1 | Metbo_1901 | Metbo_2329 | Thermosome; KEGG: mth:MTH794 chaperonin; TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | 0.696 |
| ADZ10121.1 | dnaG | Metbo_1901 | Metbo_2330 | Thermosome; KEGG: mth:MTH794 chaperonin; TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.640 |
| ADZ10121.1 | dnaK | Metbo_1901 | Metbo_0229 | Thermosome; KEGG: mth:MTH794 chaperonin; TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | Chaperone protein dnaK; Acts as a chaperone. | 0.981 |
| ADZ10121.1 | grpE | Metbo_1901 | Metbo_0230 | Thermosome; KEGG: mth:MTH794 chaperonin; TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.962 |
| ADZ10121.1 | tuf | Metbo_1901 | Metbo_2389 | Thermosome; KEGG: mth:MTH794 chaperonin; TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1. | Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.488 |
| ADZ10542.1 | ADZ08756.1 | Metbo_2329 | Metbo_0504 | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: mmg:MTBMA_c03260 Fe-S oxidoreductase; SMART: Elongator protein 3/MiaB/NifB. | 0.638 |
| ADZ10542.1 | ADZ08830.1 | Metbo_2329 | Metbo_0579 | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. | 0.619 |
