| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ10339.1 | ADZ10542.1 | Metbo_2120 | Metbo_2329 | PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein. | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | 0.458 |
| ADZ10339.1 | dnaG | Metbo_2120 | Metbo_2330 | PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein. | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.835 |
| ADZ10339.1 | eif5a | Metbo_2120 | Metbo_2348 | PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein. | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.400 |
| ADZ10339.1 | priS | Metbo_2120 | Metbo_1347 | PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.807 |
| ADZ10339.1 | spt5 | Metbo_2120 | Metbo_2249 | PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein. | NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.535 |
| ADZ10542.1 | ADZ10339.1 | Metbo_2329 | Metbo_2120 | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein. | 0.458 |
| ADZ10542.1 | dnaG | Metbo_2329 | Metbo_2330 | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.854 |
| dnaG | ADZ10339.1 | Metbo_2330 | Metbo_2120 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein. | 0.835 |
| dnaG | ADZ10542.1 | Metbo_2330 | Metbo_2329 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core. | 0.854 |
| dnaG | eif5a | Metbo_2330 | Metbo_2348 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.832 |
| dnaG | endA | Metbo_2330 | Metbo_0616 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.993 |
| dnaG | priS | Metbo_2330 | Metbo_1347 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.866 |
| dnaG | rpl13 | Metbo_2330 | Metbo_0810 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.858 |
| dnaG | rps9 | Metbo_2330 | Metbo_0811 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | KEGG: mth:MTH39 ribosomal protein S16; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.858 |
| dnaG | rrp41 | Metbo_2330 | Metbo_2185 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Exosome complex exonuclease 1; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.995 |
| dnaG | rrp42 | Metbo_2330 | Metbo_2184 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 3' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.995 |
| dnaG | spt5 | Metbo_2330 | Metbo_2249 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.869 |
| eif5a | ADZ10339.1 | Metbo_2348 | Metbo_2120 | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein. | 0.400 |
| eif5a | dnaG | Metbo_2348 | Metbo_2330 | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.832 |
| eif5a | endA | Metbo_2348 | Metbo_0616 | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.566 |