Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10554.1Oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; KEGG: mth:MTH875 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein. (317 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
     
 0.926
ADZ08588.1
Glutamine--scyllo-inositol transaminase; KEGG: mmg:MTBMA_c15650 pyridoxal phosphate-dependent enzyme; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.921
ADZ10553.1
PyrE-like protein; KEGG: mth:MTH876 orotate phosphoribosyltransferase-like protein; HAMAP: Orotate phosphoribosyltransferase-like; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.917
ADZ08979.1
PFAM: Bacterial transferase hexapeptide repeat; KEGG: mfv:Mfer_0757 acetyl / acyl transferase related protein.
  
 0.815
ADZ10556.1
PFAM: Mur ligase, central; KEGG: mfv:Mfer_1205 mur ligase middle domain protein.
 
     0.771
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.713
ADZ08973.1
PFAM: Methyltransferase type 11; KEGG: npu:Npun_F4534 methyltransferase type 11.
  
  
 0.705
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.701
ADZ10558.1
KEGG: mth:MTH871 bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase; PFAM: Inositol monophosphatase.
  
  
 0.683
ADZ08291.1
PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase.
  
  
 0.658
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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