STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10556.1PFAM: Mur ligase, central; KEGG: mfv:Mfer_1205 mur ligase middle domain protein. (447 aa)    
Predicted Functional Partners:
ADZ08290.1
Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1.
 
  
 0.975
ADZ10428.1
KEGG: mth:MTH735 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site.
 
 
 0.942
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
    0.936
nifH-2
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
    
 0.923
ADZ10429.1
Mur ligase middle domain protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; KEGG: mfv:Mfer_0762 mur ligase middle domain protein.
 
  
 0.915
ADZ10558.1
KEGG: mth:MTH871 bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase; PFAM: Inositol monophosphatase.
       0.894
pdaD
KEGG: mth:MTH870 hypothetical protein; TIGRFAM: Pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family.
 
     0.889
ADZ08935.1
UPF0288 protein; KEGG: mmg:MTBMA_c04360 peptidyl-prolyl cis-trans isomerase related protein; TIGRFAM: Uncharacterised protein family UPF0288, methanogenesis; HAMAP: Uncharacterised protein family UPF0288, methanogenesis; Belongs to the UPF0288 family.
  
   
 0.844
ADZ10653.1
TIGRFAM: Putative methanogenesis marker domain 9; KEGG: mth:MTH1014 hypothetical protein.
 
   
 0.785
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
 
 0.774
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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