STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa)    
Predicted Functional Partners:
ADZ10558.1
KEGG: mth:MTH871 bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase; PFAM: Inositol monophosphatase.
 
  
 0.990
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
  
 0.952
ADZ10556.1
PFAM: Mur ligase, central; KEGG: mfv:Mfer_1205 mur ligase middle domain protein.
  
    0.936
ADZ09239.1
PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mmg:MTBMA_c06000 nicotinamide-nucleotide adenylyltransferase.
    
 0.926
pdaD
KEGG: mth:MTH870 hypothetical protein; TIGRFAM: Pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family.
 
     0.916
ADZ09930.1
NAD(+) diphosphatase; KEGG: cce:Ccel_2937 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; NADH pyrophosphatase-like, N-terminal; Zinc ribbon, NADH pyrophosphatase.
     
 0.910
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
     
 0.718
ADZ10554.1
Oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; KEGG: mth:MTH875 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein.
  
  
 0.713
ADZ10270.1
KEGG: mst:Msp_1077 dihydrolipoamide dehydrogenase-related protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
 0.700
ADZ10553.1
PyrE-like protein; KEGG: mth:MTH876 orotate phosphoribosyltransferase-like protein; HAMAP: Orotate phosphoribosyltransferase-like; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.681
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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