| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ10585.1 | ADZ10586.1 | Metbo_2372 | Metbo_2373 | PFAM: RIO-like kinase; KEGG: mmg:MTBMA_c13870 serine/threonine protein kinase; SMART: RIO kinase. | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | 0.940 |
| ADZ10585.1 | eif1a | Metbo_2372 | Metbo_2371 | PFAM: RIO-like kinase; KEGG: mmg:MTBMA_c13870 serine/threonine protein kinase; SMART: RIO kinase. | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.983 |
| ADZ10585.1 | rnhB | Metbo_2372 | Metbo_2431 | PFAM: RIO-like kinase; KEGG: mmg:MTBMA_c13870 serine/threonine protein kinase; SMART: RIO kinase. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.501 |
| ADZ10585.1 | top6A | Metbo_2372 | Metbo_2375 | PFAM: RIO-like kinase; KEGG: mmg:MTBMA_c13870 serine/threonine protein kinase; SMART: RIO kinase. | Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.787 |
| ADZ10585.1 | top6B | Metbo_2372 | Metbo_2374 | PFAM: RIO-like kinase; KEGG: mmg:MTBMA_c13870 serine/threonine protein kinase; SMART: RIO kinase. | DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.733 |
| ADZ10586.1 | ADZ10585.1 | Metbo_2373 | Metbo_2372 | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | PFAM: RIO-like kinase; KEGG: mmg:MTBMA_c13870 serine/threonine protein kinase; SMART: RIO kinase. | 0.940 |
| ADZ10586.1 | dnaG | Metbo_2373 | Metbo_2330 | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.718 |
| ADZ10586.1 | eif1a | Metbo_2373 | Metbo_2371 | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.929 |
| ADZ10586.1 | nop10 | Metbo_2373 | Metbo_0210 | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. | 0.886 |
| ADZ10586.1 | rnhB | Metbo_2373 | Metbo_2431 | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.493 |
| ADZ10586.1 | top6A | Metbo_2373 | Metbo_2375 | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.872 |
| ADZ10586.1 | top6B | Metbo_2373 | Metbo_2374 | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.874 |
| dnaG | ADZ10586.1 | Metbo_2330 | Metbo_2373 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology. | 0.718 |
| dnaG | eif1a | Metbo_2330 | Metbo_2371 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.459 |
| dnaG | hjc | Metbo_2330 | Metbo_0311 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Resolvase, Holliday junction-type; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. | 0.716 |
| dnaG | nop10 | Metbo_2330 | Metbo_0210 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. | 0.702 |
| dnaG | pcn | Metbo_2330 | Metbo_0205 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.661 |
| dnaG | priS | Metbo_2330 | Metbo_1347 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.822 |
| dnaG | rnhB | Metbo_2330 | Metbo_2431 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.697 |
| dnaG | top6A | Metbo_2330 | Metbo_2375 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.700 |
