Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ10596.1KEGG: mth:MTH628 hypothetical protein; PFAM: Bacterial transcription activator, effector binding; SMART: Bacterial transcription activator, effector binding. (154 aa)    
Predicted Functional Partners:
ADZ10610.1
DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.691
ADZ10611.1
PFAM: RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; KEGG: mst:Msp_1375 DNA-directed RNA polymerase subunit beta''; Belongs to the RNA polymerase beta chain family.
   
   0.691
rpoD
DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.651
rpoK
DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
    
   0.651
rpoA2
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.617
ADZ10609.1
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.617
ADZ10597.1
Protein of unknown function DUF88; KEGG: mmg:MTBMA_c04840 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00288; PFAM: Domain of unknown function DUF88.
       0.475
ADZ10084.1
PFAM: 4Fe-4S binding domain; KEGG: mth:MTH221 hypothetical protein.
 
     0.458
ADZ09079.1
Regulatory protein MarR; KEGG: mmg:MTBMA_c13170 transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.
 
   
 0.400
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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