STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10597.1Protein of unknown function DUF88; KEGG: mmg:MTBMA_c04840 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00288; PFAM: Domain of unknown function DUF88. (165 aa)    
Predicted Functional Partners:
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
   
   0.664
purO
IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP.
  
     0.532
ADZ09186.1
Phosphoesterase RecJ domain protein; KEGG: mmg:MTBMA_c11580 archaea-specific RecJ-like exonuclease; PFAM: Phosphoesterase, RecJ-like; Nucleic acid binding, OB-fold, tRNA/helicase-type; Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1.
  
     0.530
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
   
   0.525
ADZ08874.1
UPF0278 protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.498
ADZ09406.1
Protein of unknown function DUF54; PFAM: Uncharacterised protein family UPF0201; KEGG: mfv:Mfer_0658 hypothetical protein; Belongs to the UPF0201 family.
  
     0.494
ADZ10082.1
PFAM: Protein of unknown function DUF166; KEGG: mth:MTH1356 hypothetical protein.
  
     0.492
ADZ10596.1
KEGG: mth:MTH628 hypothetical protein; PFAM: Bacterial transcription activator, effector binding; SMART: Bacterial transcription activator, effector binding.
       0.475
ADZ08794.1
Queuosine synthesis-like protein; PFAM: Queuosine synthesis; KEGG: mfv:Mfer_0169 queuosine synthesis.
  
     0.459
ADZ08502.1
Phosphodiesterase, MJ0936 family; KEGG: mmg:MTBMA_c16490 phosphodiesterase; TIGRFAM: Phosphodiesterase MJ0936; PFAM: Metallo-dependent phosphatase.
 
     0.450
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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