STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10643.1PFAM: Cell shape determining protein MreB/Mrl; KEGG: mth:MTH1024 rod shape-determining protein MreB. (357 aa)    
Predicted Functional Partners:
ADZ10642.1
KEGG: mmg:MTBMA_c14070 hypothetical protein.
       0.908
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.866
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.724
ADZ09225.1
Lactate utilization protein B/C; PFAM: Domain of unknown function DUF162; KEGG: mmg:MTBMA_c05900 conserved iron-sulfur cluster binding protein.
   
   0.691
ADZ10645.1
PFAM: MotA/TolQ/ExbB proton channel; KEGG: mmg:MTBMA_c14040 biopolymer transport protein.
 
   
 0.634
ADZ10428.1
KEGG: mth:MTH735 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site.
 
  
 0.623
ADZ10429.1
Mur ligase middle domain protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; KEGG: mfv:Mfer_0762 mur ligase middle domain protein.
 
  
 0.600
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.587
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
  
 0.558
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.543
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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