STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10657.1AAA ATPase central domain protein; KEGG: mth:MTH1011 ATP-dependent 26S protease regulatory subunit 8; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core. (373 aa)    
Predicted Functional Partners:
rpl2
Ribosomal protein L2, C-terminal; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
   0.662
ADZ10659.1
KEGG: mmg:MTBMA_c10960 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
     0.631
ADZ09720.1
Phosphonate-transporting ATPase; PFAM: ABC transporter-like; KEGG: mru:mru_1438 ABC transporter ATP-binding protein; SMART: ATPase, AAA+ type, core.
  
     0.535
ADZ09101.1
Xenobiotic-transporting ATPase; PFAM: ABC transporter-like; KEGG: sfu:Sfum_3988 ABC transporter related; SMART: ATPase, AAA+ type, core.
 
  
 0.534
ADZ10023.1
Phosphonate-transporting ATPase; PFAM: ABC transporter-like; KEGG: mru:mru_1438 ABC transporter ATP-binding protein; SMART: ATPase, AAA+ type, core.
  
     0.530
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
  
 
 0.514
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.512
ADZ10656.1
KEGG: msi:Msm_1725 hypothetical protein.
       0.512
rpl14
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
   
 0.511
ADZ10199.1
Xenobiotic-transporting ATPase; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; KEGG: lsp:Bsph_0315 putative multidrug export ATP-binding/permease protein; SMART: ATPase, AAA+ type, core.
 
  
 0.510
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.