| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08416.1 | ADZ08605.1 | Metbo_0164 | Metbo_0353 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.850 |
| ADZ08416.1 | ADZ08620.1 | Metbo_0164 | Metbo_0368 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mth:MTH1136 methyl viologen-reducing hydrogenase, delta subunit. | 0.999 |
| ADZ08416.1 | ADZ08952.1 | Metbo_0164 | Metbo_0701 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | TIGRFAM: CoB--CoM heterodisulphide reductase, subunit B; KEGG: mmg:MTBMA_c04500 CoB-CoM heterodisulfide reductase, subunit B; PFAM: Cysteine-rich domain. | 0.999 |
| ADZ08416.1 | ADZ09449.1 | Metbo_0164 | Metbo_1206 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | KEGG: msi:Msm_0083 heterodisulfide reductase, subunit B, HdrB; PFAM: Cysteine-rich domain. | 0.899 |
| ADZ08416.1 | ADZ09491.1 | Metbo_0164 | Metbo_1249 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | KEGG: msi:Msm_0083 heterodisulfide reductase, subunit B, HdrB; PFAM: Cysteine-rich domain. | 0.899 |
| ADZ08416.1 | ADZ10495.1 | Metbo_0164 | Metbo_2281 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.753 |
| ADZ08416.1 | ADZ10691.1 | Metbo_0164 | Metbo_2478 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | KEGG: rci:LRC438 putative heterodisulfide reductase, subunit B; PFAM: Cysteine-rich domain. | 0.911 |
| ADZ08416.1 | ADZ10692.1 | Metbo_0164 | Metbo_2479 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | PFAM: 4Fe-4S binding domain; KEGG: mpd:MCP_1991 putative CoB--CoM heterodisulfide reductase iron-sulfur subunit C. | 0.949 |
| ADZ08605.1 | ADZ08416.1 | Metbo_0353 | Metbo_0164 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | 0.850 |
| ADZ08605.1 | ADZ08620.1 | Metbo_0353 | Metbo_0368 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mth:MTH1136 methyl viologen-reducing hydrogenase, delta subunit. | 0.696 |
| ADZ08605.1 | ADZ08952.1 | Metbo_0353 | Metbo_0701 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | TIGRFAM: CoB--CoM heterodisulphide reductase, subunit B; KEGG: mmg:MTBMA_c04500 CoB-CoM heterodisulfide reductase, subunit B; PFAM: Cysteine-rich domain. | 0.765 |
| ADZ08605.1 | ADZ09448.1 | Metbo_0353 | Metbo_1205 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | Methyl-viologen-reducing hydrogenase delta subunit; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | 0.719 |
| ADZ08605.1 | ADZ09449.1 | Metbo_0353 | Metbo_1206 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | KEGG: msi:Msm_0083 heterodisulfide reductase, subunit B, HdrB; PFAM: Cysteine-rich domain. | 0.671 |
| ADZ08605.1 | ADZ09491.1 | Metbo_0353 | Metbo_1249 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | KEGG: msi:Msm_0083 heterodisulfide reductase, subunit B, HdrB; PFAM: Cysteine-rich domain. | 0.710 |
| ADZ08605.1 | ADZ10495.1 | Metbo_0353 | Metbo_2281 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.901 |
| ADZ08605.1 | ADZ10690.1 | Metbo_0353 | Metbo_2477 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | Methyl-viologen-reducing hydrogenase delta subunit; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | 0.719 |
| ADZ08605.1 | ADZ10691.1 | Metbo_0353 | Metbo_2478 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | KEGG: rci:LRC438 putative heterodisulfide reductase, subunit B; PFAM: Cysteine-rich domain. | 0.671 |
| ADZ08605.1 | ADZ10692.1 | Metbo_0353 | Metbo_2479 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | PFAM: 4Fe-4S binding domain; KEGG: mpd:MCP_1991 putative CoB--CoM heterodisulfide reductase iron-sulfur subunit C. | 0.718 |
| ADZ08620.1 | ADZ08416.1 | Metbo_0368 | Metbo_0164 | PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mth:MTH1136 methyl viologen-reducing hydrogenase, delta subunit. | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). | 0.999 |
| ADZ08620.1 | ADZ08605.1 | Metbo_0368 | Metbo_0353 | PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mth:MTH1136 methyl viologen-reducing hydrogenase, delta subunit. | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.696 |
