STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10718.1PFAM: Formylmethanofuran dehydrogenase, subunit E domain; KEGG: mbu:Mbur_0286 formylmethanofuran dehydrogenase, subunit E. (198 aa)    
Predicted Functional Partners:
ADZ10728.1
TIGRFAM: Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molydopterin dinucleotide-binding domain; KEGG: mth:MTH1552 formate dehydrogenase, alpha subunit-like protein; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding.
  
 
 0.929
cdhA
Acetyl-CoA decarbonylase/synthase complex subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
  
  
 0.776
cdhB
Acetyl-CoA decarbonylase/synthase complex subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation. Belongs to the CdhB family.
  
  
  0.756
ftr
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
     
 0.685
ADZ09514.1
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; KEGG: mfv:Mfer_1096 formylmethanofuran-tetrahydromethanopterin formyltransferase; PFAM: Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal; Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal.
     
 0.681
ADZ08737.1
PFAM: 4Fe-4S binding domain; KEGG: mth:MTH1736 formate hydrogenlyase, iron-sulfur subunit 2.
     
  0.650
ADZ08738.1
PFAM: 4Fe-4S binding domain; KEGG: mmg:MTBMA_c03120 HycB-related protein.
     
  0.650
ADZ08885.1
PFAM: Glutamate synthase, alpha subunit, C-terminal; KEGG: mfv:Mfer_0106 glutamate synthase alpha subunit domain protein.
 
  
 0.530
ADZ10082.1
PFAM: Protein of unknown function DUF166; KEGG: mth:MTH1356 hypothetical protein.
  
     0.492
ADZ08394.1
PFAM: Protein of unknown function DUF166; KEGG: mth:MTH1356 hypothetical protein.
  
     0.477
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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