STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ10722.1KEGG: mru:mru_0344 tungsten formylmethanofuran dehydrogenase subunit A FwdA; TIGRFAM: Formylmethanofuran dehydrogenase, subunit A; PFAM: Amidohydrolase 3. (569 aa)    
Predicted Functional Partners:
mtd
F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
 
   
 0.999
ADZ08416.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
   
 
 0.999
ftr
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
 
 0.999
mtrA
Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
     
 0.999
ADZ08623.1
PFAM: 4Fe-4S binding domain; KEGG: mth:MTH1133 polyferredoxin (MvhB).
      
 0.999
ADZ10721.1
TIGRFAM: Formylmethanofuran dehydrogenase subunit C; KEGG: mru:mru_0345 tungsten formylmethanofuran dehydrogenase subunit C FwdC; PFAM: Glutamate synthase, alpha subunit, C-terminal.
 
 
 0.999
ADZ10723.1
TIGRFAM: Formylmethanofuran dehydrogenase, subunit B; KEGG: msi:Msm_1412 tungsten formylmethanofuran dehydrogenase, subunit B, FwdB; PFAM: Molybdopterin oxidoreductase.
 
 
 0.999
ADZ10724.1
Molybdopterin dinucleotide-binding region; PFAM: Molydopterin dinucleotide-binding domain; KEGG: msi:Msm_1411 tungsten formylmethanofuran dehydrogenase, subunit D, FwdD.
 
 
 0.999
ADZ10725.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mru:mru_0341 tungsten formylmethanofuran dehydrogenase subunit G FwdG.
 
 
 0.999
ADZ10726.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mru:mru_0340 tungsten formylmethanofuran dehydrogenase subunit F FwdF.
  
 
 0.999
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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