| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08556.1 | ftsY | Metbo_0304 | Metbo_0548 | TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; KEGG: mth:MTH1216 pantothenate metabolism flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.518 |
| ADZ08556.1 | secG | Metbo_0304 | Metbo_2533 | TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; KEGG: mth:MTH1216 pantothenate metabolism flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein. | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | 0.402 |
| ADZ08993.1 | secG | Metbo_0742 | Metbo_2533 | PFAM: Protein of unknown function DUF2070, membrane; KEGG: mmg:MTBMA_c04800 hypothetical protein. | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | 0.402 |
| ftsY | ADZ08556.1 | Metbo_0548 | Metbo_0304 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; KEGG: mth:MTH1216 pantothenate metabolism flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein. | 0.518 |
| ftsY | secE | Metbo_0548 | Metbo_2248 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Preprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.564 |
| ftsY | secG | Metbo_0548 | Metbo_2533 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | 0.530 |
| ftsY | secY | Metbo_0548 | Metbo_0798 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.966 |
| rps6e | secE | Metbo_0606 | Metbo_2248 | KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | Preprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.831 |
| rps6e | secG | Metbo_0606 | Metbo_2533 | KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | 0.402 |
| rps6e | secY | Metbo_0606 | Metbo_0798 | KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.499 |
| secE | ftsY | Metbo_2248 | Metbo_0548 | Preprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.564 |
| secE | rps6e | Metbo_2248 | Metbo_0606 | Preprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.831 |
| secE | secG | Metbo_2248 | Metbo_2533 | Preprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | 0.536 |
| secE | secY | Metbo_2248 | Metbo_0798 | Preprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.951 |
| secG | ADZ08556.1 | Metbo_2533 | Metbo_0304 | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; KEGG: mth:MTH1216 pantothenate metabolism flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein. | 0.402 |
| secG | ADZ08993.1 | Metbo_2533 | Metbo_0742 | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | PFAM: Protein of unknown function DUF2070, membrane; KEGG: mmg:MTBMA_c04800 hypothetical protein. | 0.402 |
| secG | ftsY | Metbo_2533 | Metbo_0548 | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.530 |
| secG | rps6e | Metbo_2533 | Metbo_0606 | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.402 |
| secG | secE | Metbo_2533 | Metbo_2248 | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | Preprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.536 |
| secG | secY | Metbo_2533 | Metbo_0798 | Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.577 |
