STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MKNK2MAPK interacting serine/threonine kinase 2. (470 aa)    
Predicted Functional Partners:
MAPK1
Mitogen-activated protein kinase 1.
    
0.908
EIF4E
Eukaryotic translation initiation factor 4E.
    
 0.869
EIF4E1B
Eukaryotic translation initiation factor 4E family member 1B.
    
 0.867
ATF4
Activating transcription factor 4.
     
 0.760
EIF4E3
Eukaryotic translation initiation factor 4E family member 3.
    
 0.726
MAPK14
Mitogen-activated protein kinase 14.
  
0.704
MAPK13
Mitogen-activated protein kinase 13.
  
 
0.701
MAPK12
Mitogen-activated protein kinase 12.
  
 
0.699
MAPK11
Mitogen-activated protein kinase 11.
   
0.680
ENSDNVP00000006863
annotation not available
     
 0.665
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.