STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIAS1Protein inhibitor of activated STAT 1. (651 aa)    
Predicted Functional Partners:
SUMO1
Small ubiquitin like modifier 1.
    
 0.930
STAT3
Signal transducer and activator of transcription 3.
    
 0.909
UBE2I
Ubiquitin conjugating enzyme E2 I.
    
 0.908
KCTD2
Potassium channel tetramerization domain containing 2.
    
 0.887
SUMO2
Small ubiquitin like modifier 2.
    
 0.875
SUMO3
Small ubiquitin-related modifier 3-like.
    
 0.875
ENSDNVP00000002916
annotation not available
   
 0.865
PIAS2
Protein inhibitor of activated STAT 2.
  
 
 
0.841
PIAS4
Protein inhibitor of activated STAT 4.
  
 
0.790
UBE2N
Ubiquitin conjugating enzyme E2 N.
    
 0.769
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.