STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRF1Nuclear respiratory factor 1. (513 aa)    
Predicted Functional Partners:
PPARGC1A
PPARG coactivator 1 alpha.
   
 0.938
PPRC1
PPARG related coactivator 1.
   
 0.859
PPARGC1B
PPARG coactivator 1 beta.
     
 0.812
RBM22
RNA binding motif protein 22.
   
 0.796
TFAM
Transcription factor A, mitochondrial.
     
 0.668
SIRT1
Sirtuin 1.
    
 
 0.572
LOC112985311
Cytochrome c.
     
 0.498
ENSDNVP00000024954
annotation not available
     
 0.498
ATP5F1B
ATP synthase F1 subunit beta.
     
 0.488
GABPA
GA binding protein transcription factor subunit alpha.
     
 0.478
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.