STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIAM2TIAM Rac1 associated GEF 2. (1724 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.892
RAC2
Rac family small GTPase 2.
    
 0.858
RAC1
Rac family small GTPase 1.
    
 0.858
PARD3
Par-3 family cell polarity regulator.
    
 0.857
CD44
CD44 molecule (Indian blood group).
    
 0.849
RRAS2
RAS related 2.
    
 0.837
MRAS
Muscle RAS oncogene homolog.
    
 0.837
PRKCI
Protein kinase C iota.
    
 0.773
PRKCZ
Protein kinase C zeta.
    
 0.773
PAK3
P21 (RAC1) activated kinase 3.
    
 0.771
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.