STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC112990568Protein spire homolog 1-like. (351 aa)    
Predicted Functional Partners:
GRAP2
GRB2 related adaptor protein 2.
   
 0.870
GRB2
Growth factor receptor bound protein 2.
   
 0.812
FMN1
Formin 1.
    
 0.811
FMN2
Formin 2.
    
 0.811
NCK2
NCK adaptor protein 2.
    
 0.761
SYK
Spleen associated tyrosine kinase.
   
 0.699
ZAP70
Tyrosine-protein kinase ZAP-70.
   
 0.699
ENSDNVP00000018747
annotation not available
   
 0.674
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.673
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.673
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.