STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT6Sirtuin 6. (356 aa)    
Predicted Functional Partners:
SIRT5
Sirtuin 5.
  
0.947
SIRT1
Sirtuin 1.
  
0.946
SIRT4
Sirtuin 4.
  
  
0.938
KDM2B
Lysine demethylase 2B.
    
 0.918
KDM2A
Lysine demethylase 2A.
    
 0.918
NAMPT
Nicotinamide phosphoribosyltransferase.
     
 0.899
SIRT3
Sirtuin 3.
  
  
0.897
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.897
NUDT12
Nudix hydrolase 12.
    
 0.886
NADSYN1
NAD synthetase 1.
    
 0.878
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.