STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK5P21 (RAC1) activated kinase 5. (751 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.978
CDC42
Cell division cycle 42.
   
 0.970
NCK2
NCK adaptor protein 2.
    
 0.938
RAC2
Rac family small GTPase 2.
   
 0.921
RAC1
Rac family small GTPase 1.
   
 0.921
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.914
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.914
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.866
LIMK1
LIM domain kinase 1.
    
0.863
LIMK2
LIM domain kinase 2.
    
0.863
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.