ENSDNVP00000023357 protein (Dromaius novaehollandiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSDNVP00000023357

annotation not available (448 aa)

Predicted Functional Partners:

STRAP

0.610

PEX5L

0.438

MAB21L3

0.414

GMNC

0.414

SLC30A8

0.414

LYPLAL1

0.410

Your Current Organism:

Dromaius novaehollandiae

NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSDNVP00000023357	GMNC	ENSDNVP00000023357	ENSDNVP00000008722	annotation not available	Geminin coiled-coil domain containing.	0.414
ENSDNVP00000023357	LYPLAL1	ENSDNVP00000023357	ENSDNVP00000003367	annotation not available	Lysophospholipase like 1.	0.410
ENSDNVP00000023357	MAB21L3	ENSDNVP00000023357	ENSDNVP00000002911	annotation not available	Mab-21 like 3.	0.414
ENSDNVP00000023357	PEX5L	ENSDNVP00000023357	ENSDNVP00000023848	annotation not available	Peroxisomal biogenesis factor 5 like.	0.438
ENSDNVP00000023357	SLC30A8	ENSDNVP00000023357	ENSDNVP00000012580	annotation not available	Solute carrier family 30 member 8.	0.414
ENSDNVP00000023357	STRAP	ENSDNVP00000023357	ENSDNVP00000008269	annotation not available	Serine/threonine kinase receptor associated protein.	0.610
GMNC	ENSDNVP00000023357	ENSDNVP00000008722	ENSDNVP00000023357	Geminin coiled-coil domain containing.	annotation not available	0.414
GMNC	MAB21L3	ENSDNVP00000008722	ENSDNVP00000002911	Geminin coiled-coil domain containing.	Mab-21 like 3.	0.593
LYPLAL1	ENSDNVP00000023357	ENSDNVP00000003367	ENSDNVP00000023357	Lysophospholipase like 1.	annotation not available	0.410
LYPLAL1	SLC30A8	ENSDNVP00000003367	ENSDNVP00000012580	Lysophospholipase like 1.	Solute carrier family 30 member 8.	0.533
MAB21L3	ENSDNVP00000023357	ENSDNVP00000002911	ENSDNVP00000023357	Mab-21 like 3.	annotation not available	0.414
MAB21L3	GMNC	ENSDNVP00000002911	ENSDNVP00000008722	Mab-21 like 3.	Geminin coiled-coil domain containing.	0.593
PEX5L	ENSDNVP00000023357	ENSDNVP00000023848	ENSDNVP00000023357	Peroxisomal biogenesis factor 5 like.	annotation not available	0.438
SLC30A8	ENSDNVP00000023357	ENSDNVP00000012580	ENSDNVP00000023357	Solute carrier family 30 member 8.	annotation not available	0.414
SLC30A8	LYPLAL1	ENSDNVP00000012580	ENSDNVP00000003367	Solute carrier family 30 member 8.	Lysophospholipase like 1.	0.533
STRAP	ENSDNVP00000023357	ENSDNVP00000008269	ENSDNVP00000023357	Serine/threonine kinase receptor associated protein.	annotation not available	0.610

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.747

expected number of edges:

14

PPI enrichment p-value:

3.86e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008299

Isoprenoid biosynthetic process

3 of 12

2.02

1.41

0.0018

GO:0008360

Regulation of cell shape

3 of 37

1.53

0.8

0.0215

GO:0009252

Peptidoglycan biosynthetic process

3 of 40

1.49

0.79

0.0215

GO:0071555

Cell wall organization

3 of 57

1.34

0.74

0.0221

GO:0008610

Lipid biosynthetic process

4 of 123

1.13

0.66

0.0215

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050380

Undecaprenyl-diphosphatase activity

2 of 3

2.44

0.74

0.0457

GO:0004659

Prenyltransferase activity

2 of 5

2.22

0.72

0.0478

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3932

Undecaprenyl-diphosphatase activity, and PDZ domain 6

5 of 5

2.62

4.27

7.07e-09

CL:2406

Isoprene biosynthesis, and Polyprenyl synthetase

3 of 10

2.1

1.73

0.00043

CL:2416

Polyprenyl synthetase, and Dimethylallyl diphosphate metabolic process

2 of 5

2.22

1.03

0.0124

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

4 of 17

1.99

2.33

1.37e-05

map00550

Peptidoglycan biosynthesis

3 of 32

1.59

1.11

0.0042

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00348

Polyprenyl synthetase

2 of 2

2.62

0.91

0.0225

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