STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KNL1Kinetochore scaffold 1. (2395 aa)    
Predicted Functional Partners:
WRN
General transcription factor IIE subunit 2.
  
 0.994
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.985
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.984
ENSDNVP00000003598
annotation not available
   
 0.977
MIS12
MIS12 kinetochore complex component.
    
 0.966
XRCC3
X-ray repair cross complementing 3.
   
 0.942
BRCA2
BRCA2 DNA repair associated.
   
 0.937
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.918
FANCM
FA complementation group M.
   
 0.918
DSN1
DSN1 component of MIS12 kinetochore complex.
   
 0.916
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.