STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (646 aa)    
Predicted Functional Partners:
MAP2K5
Mitogen-activated protein kinase kinase 5.
  
0.982
CCM2
CCM2 scaffold protein.
    
 0.940
PAK2
P21 (RAC1) activated kinase 2.
    
0.894
MAP3K2
Mitogen-activated protein kinase kinase kinase 2.
  
 
 
0.883
TRAF6
TNF receptor-associated factor 6-like.
   
 0.862
PAK3
P21 (RAC1) activated kinase 3.
    
0.852
PAK1
P21 (RAC1) activated kinase 1.
    
0.852
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.842
MAP2K2
Mitogen-activated protein kinase kinase 2.
  
0.839
MAP2K1
Mitogen-activated protein kinase kinase 1.
  
0.839
Your Current Organism:
Dromaius novaehollandiae
NCBI taxonomy Id: 8790
Other names: D. novaehollandiae, Dromaius novae-hollandiae, emu
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.