STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpXZn-dependent protease with chaperone function; PFAM: Peptidase family M48; Belongs to the peptidase M48B family. (316 aa)    
Predicted Functional Partners:
EIM63937.1
PFAM: Dynamin family.
     
 0.582
EIM64740.1
PFAM: Dynamin family.
     
 0.582
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.575
EIM62851.1
Putative hydrolase or acyltransferase of alpha/beta superfamily.
 
   
 0.565
EIM64099.1
FtsH-interacting integral membrane protein; PFAM: Uncharacterised protein family UPF0005; Belongs to the BI1 family.
  
  
 0.513
EIM63011.1
Protein affecting phage T7 exclusion by the F plasmid; PFAM: FxsA cytoplasmic membrane protein.
   
    0.485
msrB
methionine-R-sulfoxide reductase/methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.484
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
  
  
 0.444
EIM63939.1
Putative membrane protein; PFAM: Rhomboid family.
 
 
 0.444
EIM62581.1
PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
    
   0.441
Your Current Organism:
Desulfobacter postgatei
NCBI taxonomy Id: 879212
Other names: D. postgatei 2ac9, Desulfobacter postgatei 2ac9, Desulfobacter postgatei DSM 2034, Desulfobacter postgatei str. 2ac9, Desulfobacter postgatei strain 2ac9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.