| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE11961.1 | AEE11964.1 | Poras_0007 | Poras_0010 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | 0.983 |
| AEE11961.1 | AEE11965.1 | Poras_0007 | Poras_0011 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | COGs: COG2875 Precorrin-4 methylase; InterPro IPR002750:IPR000878:IPR006362; KEGG: bvu:BVU_3081 precorrin-4 C11-methyltransferase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C(11)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; IMG reference gene:2504823884; PFAM: Cobalamin synthesis G C-terminus; Cobalamin biosynthesis central region; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: [...] | 0.991 |
| AEE11961.1 | AEE11966.1 | Poras_0007 | Poras_0012 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR014008; KEGG: bvu:BVU_3082 decarboxylating precorrin-6y C5,15-methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; IMG reference gene:2504823885; PFAM: Tetrapyrrole (Corrin/Porphyrin) [...] | 0.858 |
| AEE11961.1 | AEE11967.1 | Poras_0007 | Poras_0013 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878:IPR003722:IPR006363; KEGG: pru:PRU_1082 precorrin-3B C17-methyltransferase/precorrin-8X methylmutase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-3B C(17)-methyltransferase., Precorrin-8X methylmutase; SPTR: Precorrin-3B C(17)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; IMG reference gene:2504823886; PFAM: Precorrin-8X methylmutase; Tetrapyrrole (Corrin/Porphyrin) Methylases [...] | 0.974 |
| AEE11961.1 | AEE11971.1 | Poras_0007 | Poras_0017 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | Sirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: pdi:BDI_1070 anaerobic cobalt chelatase CbiK; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823890; PFAM: Cobalt chelatase (CbiK). | 0.940 |
| AEE11961.1 | cbiA | Poras_0007 | Poras_0018 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.579 |
| AEE11961.1 | cbiD | Poras_0007 | Poras_0019 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.980 |
| AEE11961.1 | cobD | Poras_0007 | Poras_0197 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.545 |
| AEE11961.1 | cobQ | Poras_0007 | Poras_0195 | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.630 |
| AEE11964.1 | AEE11961.1 | Poras_0010 | Poras_0007 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | 0.983 |
| AEE11964.1 | AEE11965.1 | Poras_0010 | Poras_0011 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | COGs: COG2875 Precorrin-4 methylase; InterPro IPR002750:IPR000878:IPR006362; KEGG: bvu:BVU_3081 precorrin-4 C11-methyltransferase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C(11)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; IMG reference gene:2504823884; PFAM: Cobalamin synthesis G C-terminus; Cobalamin biosynthesis central region; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: [...] | 0.999 |
| AEE11964.1 | AEE11966.1 | Poras_0010 | Poras_0012 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR014008; KEGG: bvu:BVU_3082 decarboxylating precorrin-6y C5,15-methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; IMG reference gene:2504823885; PFAM: Tetrapyrrole (Corrin/Porphyrin) [...] | 0.995 |
| AEE11964.1 | AEE11967.1 | Poras_0010 | Poras_0013 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878:IPR003722:IPR006363; KEGG: pru:PRU_1082 precorrin-3B C17-methyltransferase/precorrin-8X methylmutase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-3B C(17)-methyltransferase., Precorrin-8X methylmutase; SPTR: Precorrin-3B C(17)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; IMG reference gene:2504823886; PFAM: Precorrin-8X methylmutase; Tetrapyrrole (Corrin/Porphyrin) Methylases [...] | 0.999 |
| AEE11964.1 | AEE11968.1 | Poras_0010 | Poras_0014 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | PepSY-associated TM helix domain protein; InterPro IPR005625; KEGG: bfr:BF2513 hypothetical protein; PFAM: PepSY-associated TM helix; SPTR: PepSY domain protein; IMG reference gene:2504823887. | 0.669 |
| AEE11964.1 | AEE11971.1 | Poras_0010 | Poras_0017 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Sirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: pdi:BDI_1070 anaerobic cobalt chelatase CbiK; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823890; PFAM: Cobalt chelatase (CbiK). | 0.986 |
| AEE11964.1 | cbiA | Poras_0010 | Poras_0018 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.863 |
| AEE11964.1 | cbiD | Poras_0010 | Poras_0019 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.996 |
| AEE11964.1 | cobD | Poras_0010 | Poras_0197 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.795 |
| AEE11964.1 | cobQ | Poras_0010 | Poras_0195 | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.937 |
| AEE11965.1 | AEE11961.1 | Poras_0011 | Poras_0007 | COGs: COG2875 Precorrin-4 methylase; InterPro IPR002750:IPR000878:IPR006362; KEGG: bvu:BVU_3081 precorrin-4 C11-methyltransferase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C(11)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; IMG reference gene:2504823884; PFAM: Cobalamin synthesis G C-terminus; Cobalamin biosynthesis central region; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: [...] | Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK). | 0.991 |