STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEE11971.1Sirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: pdi:BDI_1070 anaerobic cobalt chelatase CbiK; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823890; PFAM: Cobalt chelatase (CbiK). (319 aa)    
Predicted Functional Partners:
AEE11965.1
COGs: COG2875 Precorrin-4 methylase; InterPro IPR002750:IPR000878:IPR006362; KEGG: bvu:BVU_3081 precorrin-4 C11-methyltransferase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C(11)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; IMG reference gene:2504823884; PFAM: Cobalamin synthesis G C-terminus; Cobalamin biosynthesis central region; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: [...]
  
 0.995
AEE11964.1
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
 
 0.985
cbiD
cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.984
AEE11967.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878:IPR003722:IPR006363; KEGG: pru:PRU_1082 precorrin-3B C17-methyltransferase/precorrin-8X methylmutase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-3B C(17)-methyltransferase., Precorrin-8X methylmutase; SPTR: Precorrin-3B C(17)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; IMG reference gene:2504823886; PFAM: Precorrin-8X methylmutase; Tetrapyrrole (Corrin/Porphyrin) Methylases [...]
 
  
 0.975
AEE11961.1
Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative sirohydrochlorin cobaltochelatase; IMG reference gene:2504823880; PFAM: Cobalt chelatase (CbiK).
 
  
 
0.939
AEE11966.1
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR014008; KEGG: bvu:BVU_3082 decarboxylating precorrin-6y C5,15-methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; IMG reference gene:2504823885; PFAM: Tetrapyrrole (Corrin/Porphyrin) [...]
 
  
 0.902
AEE11970.1
TonB-dependent receptor plug; COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: dfe:Dfer_1453 TonB-dependent receptor; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB-dependent receptor plug domain protein; IMG reference gene:2504823889; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain.
       0.810
AEE11969.1
KEGG: chu:CHU_0258 hypothetical protein; SPTR: Putative lipoprotein; IMG reference gene:2504823888.
       0.660
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.646
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.602
Your Current Organism:
Porphyromonas asaccharolytica
NCBI taxonomy Id: 879243
Other names: P. asaccharolytica DSM 20707, Porphyromonas asaccharolytica ATCC 25260, Porphyromonas asaccharolytica CCUG 7834, Porphyromonas asaccharolytica DSM 20707, Porphyromonas asaccharolytica JCM 6326, Porphyromonas asaccharolytica str. DSM 20707, Porphyromonas asaccharolytica strain DSM 20707
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