Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE12154.1COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846:IPR005843; KEGG: pgn:PGN_1189 phosphoglucomutase/phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; PRIAM: Phosphoglucosamine mutase; SPTR: Phosphoglucosamine mutase; IMG reference gene:2504824078; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; P [...] (465 aa)    
Predicted Functional Partners:
AEE12643.1
COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: pgi:PG2215 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; IMG reference gene:2504824589; PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
 
 
 0.944
AEE12591.1
COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: ppm:PPSC2_c1453 mannose-6-phosphate isomerase, class I; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Phosphomannose isomerase type I; IMG reference gene:2504824533; PFAM: Phosphomannose isomerase type I.
  
 
 0.915
AEE12155.1
RNA methyltransferase, TrmA family; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR010280:IPR001566; KEGG: pgn:PGN_1190 RNA methyltransferase; PFAM: (Uracil-5)-methyltransferase; Deoxyribonuclease/rho motif-related TRAM; SPTR: 23S rRNA (Uracil-5-)-methyltransferase RumA; TIGRFAM: 23S rRNA methyltransferase/RumA; IMG reference gene:2504824079; PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. [...]
       0.814
AEE12156.1
InterPro IPR007419; KEGG: apr:Apre_1780 BFD domain protein (2Fe-2S)-binding domain protein; PFAM: BFD-like [2Fe-2S]-binding region; SPTR: BFD domain protein (2Fe-2S)-binding domain protein; IMG reference gene:2504824080; PFAM: BFD-like [2Fe-2S] binding domain.
       0.776
dacA
Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
 
 0.666
AEE13303.1
KEGG: pgi:PG2144 hypothetical protein; SPTR: Putative membrane protein; IMG reference gene:2504825283; PFAM: Protein of unknown function (DUF2723).
 
     0.654
AEE12153.1
KEGG: pgn:PGN_1188 hypothetical protein; SPTR: Putative lipoprotein; IMG reference gene:2504824077.
       0.621
AEE12152.1
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: pgi:PG1091 DHH subfamily 1 protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: DHHA1 domain protein; IMG reference gene:2504824076; PFAM: DHH family; DHHA1 domain.
     
 0.548
AEE13208.1
Hypothetical protein; KEGG: TonB-dependent receptor; SPTR: Putative uncharacterized protein; IMG reference gene:2504825186.
  
     0.547
AEE13492.1
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: bth:BT_2058 putative isoprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; IMG reference gene:2504825488; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
     0.537
Your Current Organism:
Porphyromonas asaccharolytica
NCBI taxonomy Id: 879243
Other names: P. asaccharolytica DSM 20707, Porphyromonas asaccharolytica ATCC 25260, Porphyromonas asaccharolytica CCUG 7834, Porphyromonas asaccharolytica DSM 20707, Porphyromonas asaccharolytica JCM 6326, Porphyromonas asaccharolytica str. DSM 20707, Porphyromonas asaccharolytica strain DSM 20707
Server load: low (12%) [HD]